The New York Giants fell to the San Francisco 49ers, 34-24, in Week 9 and LB Brian Burns is our Player of the Game.

High point totals mean opportunity, and several key matchups stand out as potential fantasy goldmines in Week 10. Week 10 of the NFL season is already upon us, and the challenge of setting lineups and finding an edge in fantasy football only becomes greater than the week before.

NFL Week 10 odds, picks, predictions, TV channel, streaming information for the Sunday football game between Los Angeles Rams and San Francisco 49ers.

As Giants co-owner John Mara battles cancer, a supportive airplane banner flew over MetLife Stadium’s parking lots before Sunday’s game against the 49ers. The banner read: “MR. MARA GET WELL SOON & WATCH GIANTS NATION SHOW.” That show is a popular fan-run Giants podcast.

San Francisco 49ers defensive lineman Mykel Williams will miss the rest of the season after the first-round pick was diagnosed with torn ligaments in his right knee. Williams got hurt late in the fourth quarter of Sunday's win at the New York Giants.

In Week 6, Malik Mustapha came back. The 49ers used Sigle in a platoon with Mustapha for two games, but once Mustapha took his role back over, there were no more snaps for Sigle. The 49ers move Ji’Ayir Brown into the starting lineup and slide Jason Pinnock into the nickel, making Sigle the fourth safety.

As another Giants season looks likely to wind up outside the playoffs, the hot-seat regime of coach Brian Daboll and general manager Joe Schoen faced another airplane protest banner before Sunday’s home game against the 49ers.

The San Francisco 49ers have been winning games despite significant injuries to key players. On Sunday, first-round pick Mykel Williams suffered a season-ending knee injury in a victory over the New York Giants.