NFL Week 10 odds, picks, predictions, TV channel, streaming information for the Sunday football game between Los Angeles Rams and San Francisco 49ers.

High point totals mean opportunity, and several key matchups stand out as potential fantasy goldmines in Week 10. Week 10 of the NFL season is already upon us, and the challenge of setting lineups and finding an edge in fantasy football only becomes greater than the week before.

On a more positive note, there are some previously injured players who are set to make their return in Week 9. After being sidelined since Week 2, Minnesota will bring back quarterback J.J. McCarthy, while the Los Angeles Rams will welcome back star wideout Puka Nacua.

Bethune was called for an unnecessary roughness penalty for a tackle on QB Jaxson Dart.

The San Francisco 49ers have been winning games despite significant injuries to key players. On Sunday, first-round pick Mykel Williams suffered a season-ending knee injury in a victory over the New York Giants.

The San Francisco 49ers head to the New Jersey Meadowlands to face the New York Giants for NFL Week 9, and there are several ways to watch and stream the football game scheduled at 1 p.m. ET / 10 a.m.

San Francisco is a 2.5-point favorite in the latest 49ers vs. Giants odds from SportsLine consensus, while the over/under for total points scored is 48.5. The 49ers are -143 money line favorites (risk $143 to win $100),

Another week, another top offensive weapon bit by the injury bug for Big Blue. This time around, rookie running back Cam Skattebo was the latest name to be added to the IR, as it’s been that

In Week 6, Malik Mustapha came back. The 49ers used Sigle in a platoon with Mustapha for two games, but once Mustapha took his role back over, there were no more snaps for Sigle. The 49ers move Ji’Ayir Brown into the starting lineup and slide Jason Pinnock into the nickel, making Sigle the fourth safety.