They'll get the chance to avenge their latest loss in a matchup this week with the 49ers, who continue to be one of the least healthy teams in the league with another member of the defensive line lost for the season in Mykel Williams.

The Bills are the new class of the NFL, according to DraftKings Sportsbook oddsmakers. After beating the Chiefs 28-21 on Sunday, Buffalo took over for Kansas City as the Super Bowl favorites, sitting at +600 heading into Week 10. The Chiefs aren’t far behind with +650 odds.

Sunday, the Detroit Lions (5-3) look to get back on the winning track when they travel to our nation’s capital to take on the Washington Commanders (3-6). Heavily favored Jared Goff and co. look to take advantage of a Commanders’ squad minus its QB1, Jayden Daniels.

How to watch and listen to Sunday's New York Giants and Chicago Bears game from Soldier Field with betting lines and trends.

Week 8 of the 2025 NFL season was a historic one for betting favorites, as they went 11-2 against the spread to tie the best ATS mark for favorites in any one week since the 1970 AFL/NFL merger. In Week 9, the underdogs got their revenge in a big way.

Find the best NFL betting promos and bonus codes for Week 9. Learn about top offers available, wagering requirements and how to claim them today.

CBS Sports NFL expert Will Brinson breaks down his top Monday Night Football plays for Week 9 of the NFL season

Can Josh Allen win back-to-back league MVPs?  The Buffalo Bills superstar quarterback led the team to a massive upset win over the Kansas City Chiefs in Week 9