2025 NFL Week 10 odds, betting
Digest more
ESPN BET Sportsbook is owned and operated by PENN Entertainment, Inc. and its subsidiaries ('PENN'). ESPN BET is available in states where PENN is licensed to offer sports wagering. Must be 21+ to wager. If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 10 on a sizzling 47-29 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.
The New York Giants will take on the Chicago Bears in Week 10 hoping to halt a three-game losing streak. According to early odds at FanDuel Sportsbook, the Bears are favored by 3.5 points, while the over/under (total points) is set at 48.