Kickoff from Anfield in Liverpool is set for 3 p.m. ET. The latest Liverpool vs. Real Madrid odds list the hosts as slight +150 favorites (risk $100 to win $150) on the 90-minute money line, with Real Madrid listed as the +155 underdogs.

The league phase of the UEFA Champions League continues on Tuesday with a number of matchups, including this exciting contest between Tottenham Hotspur FC and FC København.

Mikel Arteta's Napoli come into this match after an embarrassing 2-6 loss to PSV Eindhoven. Know when and where to watch UEFA Champions League 2025-26 matchday 4 clash live

The UEFA Champions League returns this week, the action headlined by five teams who boast perfect records heading into Matchday 4 as they approach the midway point of the league phase.

Trent Alexander-Arnold returns to Anfield as Liverpool faces Real Madrid in a crucial UEFA Champions League match. Liverpool is struggling, having lost four consecutive Premier League games before a recent win against Aston Villa,